Cyclization of Free Radicals at the C-7 Position of Ethyl Indole–2-carboxylate Derivatives: an Entry to a New Class of Duocarmycin Analogues

Aryl free-radicals generated at the C-7 position of ethyl indole-2-carboxylates bearing N-allyl and propargylic groups triggered intramolecular cyclizations to furnish a new class of Duocarmycin analogues, formal ethyl pyrrolo[3,2,1-ij]quinoline-2- carboxylate derivatives, through the less favorable...

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Bibliographic Details
Main Authors: Wasim N. Abdullah, Khaled Q. Shawakfeh, Naim H. Al-Said
Format: Article
Language:English
Published: MDPI AG 2005-12-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/10/12/1446/