Charge density view on bicalutamide molecular interactions in the monoclinic polymorph and androgen receptor binding pocket

Charge density view on bicalutamide molecular interactions in the monoclinic polymorph and androgen receptor binding pocket

High-resolution single-crystal X-ray measurements of the monoclinic polymorph of bicalutamide and the aspherical atom databank approach have served as a basis for a reconstruction of the charge density distribution of the drug and its androgen receptor (AR) and albumin complexes. The contributions o...

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Bibliographic Details
Main Authors: Alexander A. Korlyukov, Maura Malinska, Anna V. Vologzhanina, Mikhail S. Goizman, Damian Trzybinski, Krzysztof Wozniak
Format: Article
Language:English
Published: International Union of Crystallography 2020-01-01
Series:IUCrJ
Subjects:
structure determination
drug discovery
protein structures
x-ray crystallography
intermolecular interactions
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252519014416

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