Horizontal cells, the odd ones out in the retina, give insights into development and disease.

Horizontal cells, the odd ones out in the retina, give insights into development and disease.

Thorough investigation of a neuronal population can help reveal key aspects regarding the nervous system and its development. The retinal horizontal cells have several extraordinary features making them particularly interesting for addressing questions regarding fate assignment and subtype specifica...

Full description

Bibliographic Details
Main Authors: Henrik Boije, Shahrzad Shirazi Fard, Per-Henrik Edqvist, Finn Hallböök
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-07-01
Series:Frontiers in Neuroanatomy
Subjects:
DNA Damage
Retina
Retinoblastoma
Zebrafish
Cancer
development
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnana.2016.00077/full
id doaj-90b693ad71ab4782accc3edb6dc6f1bd
record_format Article
spelling doaj-90b693ad71ab4782accc3edb6dc6f1bd2020-11-24T23:42:24ZengFrontiers Media S.A.Frontiers in Neuroanatomy1662-51292016-07-011010.3389/fnana.2016.00077197863Horizontal cells, the odd ones out in the retina, give insights into development and disease.Henrik Boije0Shahrzad Shirazi Fard1Per-Henrik Edqvist2Finn Hallböök3Uppsala UniversityUppsala UniversityUppsala UniversityUppsala UniversityThorough investigation of a neuronal population can help reveal key aspects regarding the nervous system and its development. The retinal horizontal cells have several extraordinary features making them particularly interesting for addressing questions regarding fate assignment and subtype specification. In this review we discuss and summarize data concerning the formation and diversity of horizontal cells, how morphology is correlated to molecular markers, and how fate assignment separates the horizontal lineage from the lineages of other retinal cell types. We discuss the novel and unique final cell cycle of horizontal cell progenitors and how it may relate to the formation of retinoblastoma.http://journal.frontiersin.org/Journal/10.3389/fnana.2016.00077/fullDNA DamageRetinaRetinoblastomaZebrafishCancerdevelopment
collection DOAJ
language English
format Article
sources DOAJ
author Henrik Boije
Shahrzad Shirazi Fard
Per-Henrik Edqvist
Finn Hallböök
spellingShingle Henrik Boije
Shahrzad Shirazi Fard
Per-Henrik Edqvist
Finn Hallböök
Horizontal cells, the odd ones out in the retina, give insights into development and disease.
Frontiers in Neuroanatomy
DNA Damage
Retina
Retinoblastoma
Zebrafish
Cancer
development
author_facet Henrik Boije
Shahrzad Shirazi Fard
Per-Henrik Edqvist
Finn Hallböök
author_sort Henrik Boije
title Horizontal cells, the odd ones out in the retina, give insights into development and disease.
title_short Horizontal cells, the odd ones out in the retina, give insights into development and disease.
title_full Horizontal cells, the odd ones out in the retina, give insights into development and disease.
title_fullStr Horizontal cells, the odd ones out in the retina, give insights into development and disease.
title_full_unstemmed Horizontal cells, the odd ones out in the retina, give insights into development and disease.
title_sort horizontal cells, the odd ones out in the retina, give insights into development and disease.
publisher Frontiers Media S.A.
series Frontiers in Neuroanatomy
issn 1662-5129
publishDate 2016-07-01
description Thorough investigation of a neuronal population can help reveal key aspects regarding the nervous system and its development. The retinal horizontal cells have several extraordinary features making them particularly interesting for addressing questions regarding fate assignment and subtype specification. In this review we discuss and summarize data concerning the formation and diversity of horizontal cells, how morphology is correlated to molecular markers, and how fate assignment separates the horizontal lineage from the lineages of other retinal cell types. We discuss the novel and unique final cell cycle of horizontal cell progenitors and how it may relate to the formation of retinoblastoma.
topic DNA Damage
Retina
Retinoblastoma
Zebrafish
Cancer
development
url http://journal.frontiersin.org/Journal/10.3389/fnana.2016.00077/full
work_keys_str_mv AT henrikboije horizontalcellstheoddonesoutintheretinagiveinsightsintodevelopmentanddisease
AT shahrzadshirazifard horizontalcellstheoddonesoutintheretinagiveinsightsintodevelopmentanddisease
AT perhenrikedqvist horizontalcellstheoddonesoutintheretinagiveinsightsintodevelopmentanddisease
AT finnhallbook horizontalcellstheoddonesoutintheretinagiveinsightsintodevelopmentanddisease
_version_ 1725504685014515712

Similar Items