The Use of a Novel Heart Failure Agent in the Treatment of Pregnancy-Associated Cardiomyopathy

Peripartum cardiomyopathy is an uncommon, pregnancy-related form of dilated cardiomyopathy that is associated with development of new-onset left ventricular dysfunction. Its etiology is presently unknown, but current standard of care involves the use of typical drug therapy for the treatment of hear...

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Main Authors: Vamsi C. Gaddipati, Aarti A. Patel, Adam J. Cohen
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2017/9561405
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spelling doaj-90a3951d38584e5eab5d9ad62faad30c2020-11-24T20:47:57ZengHindawi LimitedCase Reports in Cardiology2090-64042090-64122017-01-01201710.1155/2017/95614059561405The Use of a Novel Heart Failure Agent in the Treatment of Pregnancy-Associated CardiomyopathyVamsi C. Gaddipati0Aarti A. Patel1Adam J. Cohen2Department of Cardiovascular Sciences, Morsani College of Medicine, University of South Florida, Tampa, FL, USADepartment of Cardiovascular Sciences, Morsani College of Medicine, University of South Florida, Tampa, FL, USADepartment of Cardiovascular Sciences, Morsani College of Medicine, University of South Florida, Tampa, FL, USAPeripartum cardiomyopathy is an uncommon, pregnancy-related form of dilated cardiomyopathy that is associated with development of new-onset left ventricular dysfunction. Its etiology is presently unknown, but current standard of care involves the use of typical drug therapy for the treatment of heart failure. Pregnancy-associated cardiomyopathy (PACM) is a similar condition that refers to patients who develop such symptoms prior to the last month of pregnancy. We report the case of a nulliparous Caucasian female who develops early, severe PACM during her first pregnancy with postpartum persistence of New York Heart Association class II-III symptoms despite medical therapy. The use of the novel heart failure agent, sacubitril/valsartan (Entresto), is initiated with near-complete resolution of her symptoms.http://dx.doi.org/10.1155/2017/9561405
collection DOAJ
language English
format Article
sources DOAJ
author Vamsi C. Gaddipati
Aarti A. Patel
Adam J. Cohen
spellingShingle Vamsi C. Gaddipati
Aarti A. Patel
Adam J. Cohen
The Use of a Novel Heart Failure Agent in the Treatment of Pregnancy-Associated Cardiomyopathy
Case Reports in Cardiology
author_facet Vamsi C. Gaddipati
Aarti A. Patel
Adam J. Cohen
author_sort Vamsi C. Gaddipati
title The Use of a Novel Heart Failure Agent in the Treatment of Pregnancy-Associated Cardiomyopathy
title_short The Use of a Novel Heart Failure Agent in the Treatment of Pregnancy-Associated Cardiomyopathy
title_full The Use of a Novel Heart Failure Agent in the Treatment of Pregnancy-Associated Cardiomyopathy
title_fullStr The Use of a Novel Heart Failure Agent in the Treatment of Pregnancy-Associated Cardiomyopathy
title_full_unstemmed The Use of a Novel Heart Failure Agent in the Treatment of Pregnancy-Associated Cardiomyopathy
title_sort use of a novel heart failure agent in the treatment of pregnancy-associated cardiomyopathy
publisher Hindawi Limited
series Case Reports in Cardiology
issn 2090-6404
2090-6412
publishDate 2017-01-01
description Peripartum cardiomyopathy is an uncommon, pregnancy-related form of dilated cardiomyopathy that is associated with development of new-onset left ventricular dysfunction. Its etiology is presently unknown, but current standard of care involves the use of typical drug therapy for the treatment of heart failure. Pregnancy-associated cardiomyopathy (PACM) is a similar condition that refers to patients who develop such symptoms prior to the last month of pregnancy. We report the case of a nulliparous Caucasian female who develops early, severe PACM during her first pregnancy with postpartum persistence of New York Heart Association class II-III symptoms despite medical therapy. The use of the novel heart failure agent, sacubitril/valsartan (Entresto), is initiated with near-complete resolution of her symptoms.
url http://dx.doi.org/10.1155/2017/9561405
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