Nicotinamide Promotes Cell Survival and Differentiation as Kinase Inhibitor in Human Pluripotent Stem Cells

Summary: Nicotinamide, the amide form of vitamin B3, is widely used in disease treatments and stem cell applications. However, nicotinamide's impact often cannot be attributed to its nutritional functions. In a vitamin screen, we find that nicotinamide promotes cell survival and differentiation...

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Bibliographic Details
Main Authors: Ya Meng, Zhili Ren, Faxiang Xu, Xiaoxiao Zhou, Chengcheng Song, Vivien Ya-Fan Wang, Weiwei Liu, Ligong Lu, James A. Thomson, Guokai Chen
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118304466