Sporothrix schenckii Immunization, but Not Infection, Induces Protective Th17 Responses Mediated by Circulating Memory CD4+ T Cells

Sporothrix schenckii Immunization, but Not Infection, Induces Protective Th17 Responses Mediated by Circulating Memory CD4+ T Cells

Sporotrichosis is a chronic subcutaneous mycosis caused by the Sporothrix schenckii species complex and it is considered an emerging opportunistic infection in countries with tropical and subtropical climates. The host’s immune response has a main role in the development of this disease. However, it...

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Bibliographic Details
Main Authors: Alberto García-Lozano, Conchita Toriello, Laura Antonio-Herrera, Laura C. Bonifaz
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Microbiology
Subjects:
Sporothrix schenckii
CD4 T cell memory development and survival
skin immunization
cholera toxin
Th1/Th17 immunity
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01275/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01275/full

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