DIAGNOSTIC AND PROGNOSTIC VALUE OF ALKALINE PHOSPHATASE OF NEUTROPHILS AT THE ACUTE PANCREATITIS

• Main Authors: M. A. Shevlyaeva, G. K. Karipidi, S. V. Avakimyan, E. G. Ermolenko, V. A. Avakimyan, I. G. Proskuryakov
• Format: Article
• Language: Russian
• Published: Scientific Сentre for Family Health and Human Reproduction Problems 2012-07-01
• Series: Acta Biomedica Scientifica
• Subjects: alkaline phosphatase; index of activity of alkaline of neutrophils; acute pancreatitis; complications of acute pancreatitis
• Online Access: https://www.actabiomedica.ru/jour/article/view/990
• ISSN: 2541-9420; 2587-9596

We examined 1546 patients with, acute pancreatitis. Activity of alkaline phosphatase (АР) of neutrophils was studied in dynamics in 227 patients with, acute pancreatitis. The study was conducted on the 1st, 3rd, 5th, 7—10th days at the conservative therapy and. on the 1st, 2nd, 3rd, 5th, 7th, 10th and. 12th days after the operation, and. then — as necessary. Activity of АР of neutrophils in patients with acute pancreatitis regardless of the degree of gravity is reliably increased, and. the more severe disease process is the higher activity of alkaline phosphatase of neutrophils is. IAAN has more diagnostic and. prognostic value. When interpreting the AAN index it is expedient to mark out two values of IAAN from our point of view. The first value is when IAAN is in the range from +1 to 0, it shows that destructive process is unlikely and. the patient needs conservative treatment. The second, value is a negative value of IAAN from 0 to 1. When using these values of IAAN destructive process doesn't cause doubts and. these patients need surgeries.