INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS

A study was undertaken to investigate the role of placenta in transferring drugs containing bromine to the infant. 20 pregnant subjects were given bromine as KBr (500 mg/50 Kg weight) 10h before the delivery the bromine content of the serum in the mother and the child was estimated by neutron.. 13...

Full description

Bibliographic Details
Main Authors: Z. Abedinzadeh, Z.Khalkhali
Format: Article
Language:English
Published: Tehran University of Medical Sciences 1980-09-01
Series:Acta Medica Iranica
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/135
id doaj-907fd58769074144a4930ee19de30792
record_format Article
spelling doaj-907fd58769074144a4930ee19de307922020-11-25T02:35:51ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96941980-09-01223INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS Z. Abedinzadeh0 Z.Khalkhali1 A study was undertaken to investigate the role of placenta in transferring drugs containing bromine to the infant. 20 pregnant subjects were given bromine as KBr (500 mg/50 Kg weight) 10h before the delivery the bromine content of the serum in the mother and the child was estimated by neutron.. 13 lrradlated at 2xlO activation analysis. Samples were -2 -1 n em 5 for a period of one hour. A Ge (Li) detector connected to an 800 channel analyser 82 was used for measuring Br photopeaks. In 72% of the cases the distribution of bromine in both mother and child was equal, revealing a transfer across the placenta of the intaken drug. https://acta.tums.ac.ir/index.php/acta/article/view/135
collection DOAJ
language English
format Article
sources DOAJ
author Z. Abedinzadeh
Z.Khalkhali
spellingShingle Z. Abedinzadeh
Z.Khalkhali
INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS
Acta Medica Iranica
author_facet Z. Abedinzadeh
Z.Khalkhali
author_sort Z. Abedinzadeh
title INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS
title_short INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS
title_full INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS
title_fullStr INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS
title_full_unstemmed INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS
title_sort investigation of the role of placenta in transfer of bromine containing drugs to infants
publisher Tehran University of Medical Sciences
series Acta Medica Iranica
issn 0044-6025
1735-9694
publishDate 1980-09-01
description A study was undertaken to investigate the role of placenta in transferring drugs containing bromine to the infant. 20 pregnant subjects were given bromine as KBr (500 mg/50 Kg weight) 10h before the delivery the bromine content of the serum in the mother and the child was estimated by neutron.. 13 lrradlated at 2xlO activation analysis. Samples were -2 -1 n em 5 for a period of one hour. A Ge (Li) detector connected to an 800 channel analyser 82 was used for measuring Br photopeaks. In 72% of the cases the distribution of bromine in both mother and child was equal, revealing a transfer across the placenta of the intaken drug.
url https://acta.tums.ac.ir/index.php/acta/article/view/135
work_keys_str_mv AT zabedinzadeh investigationoftheroleofplacentaintransferofbrominecontainingdrugstoinfants
AT zkhalkhali investigationoftheroleofplacentaintransferofbrominecontainingdrugstoinfants
_version_ 1724803005208854528