INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS
A study was undertaken to investigate the role of placenta in transferring drugs containing bromine to the infant. 20 pregnant subjects were given bromine as KBr (500 mg/50 Kg weight) 10h before the delivery the bromine content of the serum in the mother and the child was estimated by neutron.. 13...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
1980-09-01
|
| Series: | Acta Medica Iranica |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/135 |
| Summary: | A study was undertaken to investigate the role of placenta in transferring drugs containing bromine to the infant. 20 pregnant subjects were given bromine as KBr (500 mg/50 Kg weight) 10h before the delivery the bromine content of the serum in the mother and the child was estimated by neutron.. 13 lrradlated at 2xlO activation analysis. Samples were -2 -1 n em 5 for a period of one hour. A Ge (Li) detector connected to an 800 channel analyser 82 was used for measuring Br photopeaks. In 72% of the cases the distribution of bromine in both mother and child was equal, revealing a transfer across the placenta of the intaken drug.
|
|---|---|
| ISSN: | 0044-6025 1735-9694 |