IFI16 Preferentially Binds to DNA with Quadruplex Structure and Enhances DNA Quadruplex Formation.

IFI16 Preferentially Binds to DNA with Quadruplex Structure and Enhances DNA Quadruplex Formation.

Interferon-inducible protein 16 (IFI16) is a member of the HIN-200 protein family, containing two HIN domains and one PYRIN domain. IFI16 acts as a sensor of viral and bacterial DNA and is important for innate immune responses. IFI16 binds DNA and binding has been described to be DNA length-dependen...

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Bibliographic Details
Main Authors: Lucia Hároníková, Jan Coufal, Iva Kejnovská, Eva B Jagelská, Miroslav Fojta, Petra Dvořáková, Petr Muller, Borivoj Vojtesek, Václav Brázda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4900677?pdf=render

Internet

http://europepmc.org/articles/PMC4900677?pdf=render

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