Adipocyte DIO2 Expression Increases in Human Obesity but Is Not Related to Systemic Insulin Sensitivity

Adipocyte DIO2 Expression Increases in Human Obesity but Is Not Related to Systemic Insulin Sensitivity

Deiodinase type II (D2), encoded by DIO2, catalyzes the conversion of T4 to bioactive T3. T3 not only stimulates adaptive thermogenesis but also affects adipose tissue (AT) lipid accumulation, mitochondrial function, inflammation, and potentially systemic metabolism. Although better defined in brown...

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Bibliographic Details
Main Authors:	David Bradley, Joey Liu, Alecia Blaszczak, Valerie Wright, Anahita Jalilvand, Bradley Needleman, Sabrena Noria, David Renton, Willa Hsueh
Format:	Article
Language:	English
Published:	Hindawi Limited 2018-01-01
Series:	Journal of Diabetes Research
Online Access:	http://dx.doi.org/10.1155/2018/2464652

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