Cryptococcal antigen positivity combined with the percentage of HIV-seropositive samples with CD4 counts <100 cells/μl identifies districts in South Africa with advanced burden of disease.

INTRODUCTION:Cryptococcal meningitis (CM) is an opportunistic fungal disease with a high mortality among HIV-positive patients with severe immunosuppression (CD4 count <100 cells/μl). Reflexed screening for cryptococcal antigen (CrAg) in remnant blood samples was initially piloted at selected CD4...

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Bibliographic Details
Main Authors: Lindi-Marie Coetzee, Naseem Cassim, Charlotte Sriruttan, Mabatho Mhlanga, Nelesh P Govender, Deborah Kim Glencross
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5997320?pdf=render