Neuroinvasive Infection from O117:K52:H-Escherichia coli following Acute Pyelonephritis

Spontaneous or nosocomial Escherichia coli meningitis remains rare in healthy adults but is still carrying a high mortality rate despite adapted antimicrobial treatment for susceptible strains. A 39-year-old woman was admitted to the hospital with severe subarachnoid haemorrhage complicated by acute...

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Main Authors: H. Cromlin, H. Rodriguez-Villalobos, A. Deplano, T. Duprez, P. Hantson
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2017/8976754
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spelling doaj-9046b268a49c4d0bb9ecc0f0575c5aff2020-11-24T21:00:03ZengHindawi LimitedCase Reports in Infectious Diseases2090-66252090-66332017-01-01201710.1155/2017/89767548976754Neuroinvasive Infection from O117:K52:H-Escherichia coli following Acute PyelonephritisH. Cromlin0H. Rodriguez-Villalobos1A. Deplano2T. Duprez3P. Hantson4Department of Intensive Care, Université Catholique de Louvain, Cliniques Universitaires Saint-Luc, Brussels, BelgiumLaboratory of Microbiology, Université Catholique de Louvain, Cliniques Universitaires Saint-Luc, Brussels, BelgiumLaboratory of Microbiology, Cliniques Universitaires de Bruxelles, Brussels, BelgiumDepartment of Neuroradiology, Université Catholique de Louvain, Cliniques Universitaires Saint-Luc, Brussels, BelgiumDepartment of Intensive Care, Université Catholique de Louvain, Cliniques Universitaires Saint-Luc, Brussels, BelgiumSpontaneous or nosocomial Escherichia coli meningitis remains rare in healthy adults but is still carrying a high mortality rate despite adapted antimicrobial treatment for susceptible strains. A 39-year-old woman was admitted to the hospital with severe subarachnoid haemorrhage complicated by acute hydrocephalus. On hospital day 10, she developed Streptococcus anginosus septicaemia and urinary tract infection due to a multisensitive strain of E. coli. This infection was successfully controlled by antimicrobial therapy. As a late complication in the neurosurgical ward (day 39), she developed fever, alteration of consciousness, and shock, leading to the diagnosis of bacterial meningitis. The culture of blood, cerebrospinal fluid, and urine grew positive for a multisensitive E. coli. The strain was identified as O117:K52:H, a serotype that was until now never associated with acute meningitis or brain abscesses. The source appeared to be the urinary tract with the demonstration of acute pyelonephritis. The patient died on day 94 from delayed complications of multiple brain abscesses.http://dx.doi.org/10.1155/2017/8976754
collection DOAJ
language English
format Article
sources DOAJ
author H. Cromlin
H. Rodriguez-Villalobos
A. Deplano
T. Duprez
P. Hantson
spellingShingle H. Cromlin
H. Rodriguez-Villalobos
A. Deplano
T. Duprez
P. Hantson
Neuroinvasive Infection from O117:K52:H-Escherichia coli following Acute Pyelonephritis
Case Reports in Infectious Diseases
author_facet H. Cromlin
H. Rodriguez-Villalobos
A. Deplano
T. Duprez
P. Hantson
author_sort H. Cromlin
title Neuroinvasive Infection from O117:K52:H-Escherichia coli following Acute Pyelonephritis
title_short Neuroinvasive Infection from O117:K52:H-Escherichia coli following Acute Pyelonephritis
title_full Neuroinvasive Infection from O117:K52:H-Escherichia coli following Acute Pyelonephritis
title_fullStr Neuroinvasive Infection from O117:K52:H-Escherichia coli following Acute Pyelonephritis
title_full_unstemmed Neuroinvasive Infection from O117:K52:H-Escherichia coli following Acute Pyelonephritis
title_sort neuroinvasive infection from o117:k52:h-escherichia coli following acute pyelonephritis
publisher Hindawi Limited
series Case Reports in Infectious Diseases
issn 2090-6625
2090-6633
publishDate 2017-01-01
description Spontaneous or nosocomial Escherichia coli meningitis remains rare in healthy adults but is still carrying a high mortality rate despite adapted antimicrobial treatment for susceptible strains. A 39-year-old woman was admitted to the hospital with severe subarachnoid haemorrhage complicated by acute hydrocephalus. On hospital day 10, she developed Streptococcus anginosus septicaemia and urinary tract infection due to a multisensitive strain of E. coli. This infection was successfully controlled by antimicrobial therapy. As a late complication in the neurosurgical ward (day 39), she developed fever, alteration of consciousness, and shock, leading to the diagnosis of bacterial meningitis. The culture of blood, cerebrospinal fluid, and urine grew positive for a multisensitive E. coli. The strain was identified as O117:K52:H, a serotype that was until now never associated with acute meningitis or brain abscesses. The source appeared to be the urinary tract with the demonstration of acute pyelonephritis. The patient died on day 94 from delayed complications of multiple brain abscesses.
url http://dx.doi.org/10.1155/2017/8976754
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