Estrogen markedly reduces circulating low-density neutrophils and enhances pro-tumoral gene expression in neutrophil of tumour-bearing mice

Abstract Background Neutrophils are important for immune surveillance of tumour cells. Neutrophils may also be epigenetically programmed in the tumour microenvironment to promote tumour progression. In addition to the commonly known high-density neutrophils (HDN) based on their separation on density...

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Bibliographic Details
Main Authors: Chew Leng Lim, Valerie C.-L. Lin
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-021-08751-2