Aristolochic acid causes albuminuria by promoting mitochondrial DNA damage and dysfunction in podocyte.

Aristolochic acid causes albuminuria by promoting mitochondrial DNA damage and dysfunction in podocyte.

Aristolochic acid nephropathy, initially found in patients intaking of slimming herbs containing aristolochic acid (AA), was previously considered as a progressive renal interstitial fibrosis and urothelial malignancy. However, the presence of albuminuria in some patients with AAN suggests that AA m...

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Bibliographic Details
Main Authors: Yang Zhou, Xueqin Bian, Li Fang, Weichun He, Chunsun Dai, Junwei Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3862730?pdf=render

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