Role of individual subunits of the Neurospora crassa CSN complex in regulation of deneddylation and stability of cullin proteins.

The Cop9 signalosome (CSN) is an evolutionarily conserved multifunctional complex that controls ubiquitin-dependent protein degradation in eukaryotes. We found seven CSN subunits in Neurospora crassa in a previous study, but only one subunit, CSN-2, was functionally characterized. In this study, we...

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Bibliographic Details
Main Authors: Jiyong Wang, Qiwen Hu, Huijie Chen, Zhipeng Zhou, Weihua Li, Ying Wang, Shaojie Li, Qun He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2996332?pdf=render