Synthesis and investigation of a radioiodinated F3 peptide analog as a SPECT tumor imaging radioligand.

Synthesis and investigation of a radioiodinated F3 peptide analog as a SPECT tumor imaging radioligand.

A radioiodinated derivative of the tumor-homing F3 peptide, (N-(2-{3-[(125)I]Iodobenzoyl}aminoethyl)maleimide-F3Cys peptide, [(125)I]IBMF3 was developed for investigation as a SPECT tumor imaging radioligand. For this purpose, we custom synthesized a modified F3 peptide analog (F3Cys) incorporating...

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Bibliographic Details
Main Authors: Mahaveer S Bhojani, Rajesh Ranga, Gary D Luker, Alnawaz Rehemtulla, Brian D Ross, Marcian E Van Dort
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3139646?pdf=render

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