Gender Difference of Gut Microbiota in Liver Diseases

• Main Author: Ki Tae Suk
• Format: Article
• Language: English
• Published: Jin Publishing & Printing Co. 2021-07-01
• Series: The Korean Journal of Gastroenterology
• Subjects: gender; liver; androgen; estrogen; treatment
• Online Access: https://www.kjg.or.kr/journal/view.html?uid=5724&vmd=Full

Although sexual difference medicine is a relatively new concept, it is currently an important research area because different treatments may be required according to gender. Gender-related differences in the epidemiology, progression, and treatment strategies of chronic liver disease has been known for a long time, but there are few meaningful studies in most epidemiologic and clinical studies, but gender differences in pharmacological treatment have been associated with dose, administration timing, and incidence of drug side effects. Until now, the liver expresses androgen and estrogen receptors, so there are gender differences due to gene expression patterns, immune responses, and metabolism depending on sex hormones.