Prognostic significance of circulating PD-1, PD-L1, pan-BTN3As, BTN3A1 and BTLA in patients with pancreatic adenocarcinoma

Prognostic significance of circulating PD-1, PD-L1, pan-BTN3As, BTN3A1 and BTLA in patients with pancreatic adenocarcinoma

PDAC is one of the most heterogeneous cancers with low chemotherapeutic sensitivity due to a dense stroma, a weak vasculature and significant biological aggressivity. In cancer, suppressive immune checkpoints are often hyper-activated to ensure an effective evasion of tumor cells from immune surveil...

Full description

Bibliographic Details
Main Authors: Benjamin Bian, Daniele Fanale, Nelson Dusetti, Julie Roque, Sonia Pastor, Anne-Sophie Chretien, Lorena Incorvaia, Antonio Russo, Daniel Olive, Juan Iovanna
Format: Article
Language:English
Published: Taylor & Francis Group 2019-04-01
Series:OncoImmunology
Subjects:
immune checkpoint
pancreatic cancer
outcome
butyrophilin 3a
programmed cell death-1
programmed cell death ligand-1
b and t lymphocyte attenuator
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1561120

Internet

http://dx.doi.org/10.1080/2162402X.2018.1561120

Similar Items