Enhancement of Purkinje Neuronal Excitability by the Inhibition of Fast Voltage Gated K+ Channel Function in Ataxic Rats
Objective: The purpose of this study was to investigate the role of fast inactivating (IA) voltage dependent potassium channels in shaping the discharge activity of cerebellarPurkinje cells (PCs) in ataxic rats.Materials and Methods: Male Sprauge-Dawley rats (40-60 g) were used in this study. Ataxia...
Main Authors: | I. Goudarzi, M.R. Kaffashian, M. Janahmadi, Y. Fathollahi, S. Hajizadeh |
---|---|
Format: | Article |
Language: | English |
Published: |
Royan Institute (ACECR), Tehran
2008-01-01
|
Series: | Cell Journal |
Subjects: | |
Online Access: | http://celljournal.org/library/upload/article/Jan%20Ahmadi.pdf |
Similar Items
-
A quantitative framework for whole-body coordination reveals specific deficits in freely walking ataxic mice
by: Ana S Machado, et al.
Published: (2015-10-01) -
Ankfy1 Is Involved in the Maintenance of Cerebellar Purkinje Cells
by: Liansheng Chang, et al.
Published: (2021-03-01) -
Infant and adult SCA13 mutations differentially affect Purkinje cell excitability, maturation, and viability in vivo
by: Jui-Yi Hsieh, et al.
Published: (2020-07-01) -
Purkinje Cell Signaling Deficits in Animal Models of Ataxia
by: Eriola Hoxha, et al.
Published: (2018-04-01) -
Spinocerebellar ataxia: miRNAs expose biological pathways underlying pervasive Purkinje cell degeneration
by: Rogier van der Stijl, et al.
Published: (2017-12-01)