Synthesis and Antimicrobial activity of 2-Chloroquinoline Incorporated Pyrazoline Derivatives.

• Main Authors: Bibhu P Panda, Rajiv kumar, Suresh Kumar, Sushma Drabu, Sandhya Bawa
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2009-12-01
• Series: Journal of Pharmacy and Bioallied Sciences
• Subjects: Pyrazoline, 2-chloroquinoline, antimicrobial activity
• Online Access: http://opubs.com/jpbs/index.php/jpbs/article/view/18
• ISSN: 0975-7406

<div>A series of 2-chloroquinoline containing pyrazoline derivatives were synthesized and screened for their antimicrobial</div><div>activity against a panel of bacterial and fungal strains by cup plate method. The structures of newly synthesized compound</div><div>were established on the basis of spectral data obtained from the FTIR, 1H & 13C-NMR and mass spectrometry.</div><div>Among the compound tested 3,4-dichloro derivatives were comparatively more active in antimicrobial screening with</div><div>respect to their 3,4-dimethoxy analogue.</div>