Identification of eugenol as the major determinant of GABAA-receptor activation by aqueous Syzygium aromaticum L. (clove buds) extract

Identification of eugenol as the major determinant of GABAA-receptor activation by aqueous Syzygium aromaticum L. (clove buds) extract

The spice Syzygium aromaticum L. (clove buds) exerts topical anesthetic and analgesic effects. Since GABAA receptors are an emerging drug target for pain treatment, the effects of aqueous clove extracts on the human α1β2-GABAA receptor were tested by two-electrode voltage clamp technique applying a...

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Bibliographic Details
Main Authors:	Sümeyye Sahin, Volker Eulenburg, Anja Heinlein, Carmen Villmann, Monika Pischetsrieder
Format:	Article
Language:	English
Published:	Elsevier 2017-10-01
Series:	Journal of Functional Foods
Subjects:	Acetyleugenol Analgesic activity Clove buds Eugenol GABAA receptor Two-electrode voltage clamp technique
Online Access:	http://www.sciencedirect.com/science/article/pii/S1756464617304978

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