Anti-malarial effect of 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one and green tea extract on erythrocyte-stage Plasmodium berghei in mice

Anti-malarial effect of 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one and green tea extract on erythrocyte-stage Plasmodium berghei in mice

Objective: To examine the efficacy of 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one (CM1) iron chelator and green tea extract (GTE) as anti-malarial activity in Plasmodium berghei (P. berghei) infected mice. Methods: The CM1 (0–100 mg/kg/day) and GTE (0–100 mg (−)-epigallocatechin 3-gall...

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Bibliographic Details
Main Authors: Phitsinee Thipubon, Wachiraporn Tipsuwan, Chairat Uthaipibull, Sineenart Santitherakul, Somdet Srichairatanakool
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-11-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
Plasmodium
Antimalarial drug
Green tea
Iron chelator
Hydroxypyridinone
Online Access:http://www.sciencedirect.com/science/article/pii/S2221169115001872

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