Mechanism of chiral proofreading during translation of the genetic code

Mechanism of chiral proofreading during translation of the genetic code

The biological macromolecular world is homochiral and effective enforcement and perpetuation of this homochirality is essential for cell survival. In this study, we present the mechanistic basis of a configuration-specific enzyme that selectively removes D-amino acids erroneously coupled to tRNAs. T...

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Bibliographic Details
Main Authors: Sadeem Ahmad, Satya Brata Routh, Venu Kamarthapu, Jisha Chalissery, Sowndarya Muthukumar, Tanweer Hussain, Shobha P Kruparani, Mandar V Deshmukh, Rajan Sankaranarayanan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-12-01
Series:eLife
Subjects:
homochirality
proofreading
enzyme mechanism
translation
Online Access:https://elifesciences.org/articles/01519

Internet

https://elifesciences.org/articles/01519

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