Differences in the Early Development of Human and Mouse Embryonic Stem Cells.

We performed a systematic analysis of gene expression features in early (10-21 days) development of human vs mouse embryonic cells (hESCs vs mESCs). Many development features were found to be conserved, and a majority of differentially regulated genes have similar expression change in both organisms...

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Bibliographic Details
Main Authors: R Gabdoulline, W Kaisers, A Gaspar, K Meganathan, M X Doss, S Jagtap, J Hescheler, A Sachinidis, H Schwender
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4608779?pdf=render