Manuka honey enhanced sensitivity of HepG2, hepatocellular carcinoma cells, for Doxorubicin and induced apoptosis through inhibition of Wnt/β-catenin and ERK1/2

Manuka honey enhanced sensitivity of HepG2, hepatocellular carcinoma cells, for Doxorubicin and induced apoptosis through inhibition of Wnt/β-catenin and ERK1/2

Abstract Background Recently, there is increasing awareness focused on the identification of naturally occurring anticancer agents derived from natural products. Manuka honey (MH) has been recognized for its biological properties as antimicrobial, antioxidant, and anticancer properties. However, its...

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Bibliographic Details
Main Authors: Heba R. Al Refaey, Al-Sayeda A. Newairy, Mayssaa M. Wahby, Chris Albanese, Mohamed Elkewedi, Muhammad Umer Choudhry, Ahmed S. Sultan
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Biological Research
Subjects:
Manuka honey
Doxorubicin
Hepatocellular carcinoma cells
Apoptosis Induction
Online Access:https://doi.org/10.1186/s40659-021-00339-1

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