A little-known new components of the appetite control

• Main Authors: Marcin Nylec, Magdalena Olszanecka-Glinianowicz
• Format: Article
• Language: English
• Published: Index Copernicus International S.A. 2010-06-01
• Series: Postępy Higieny i Medycyny Doświadczalnej
• Subjects: regulacja apetytu; QRFP-43; TLQP-21; ksenina
• Online Access: http://journals.indexcopernicus.com/fulltxt.php?ICID=912241

Appetite control is a complex process regulated by both neurotransmitters, such as: appetite- increasing neuropeptide Y (NPY), Agouti related peptide (AgRP), orexins A and B, as well as appetite-suppressing propiomelanocortin (POMC) and a peptide (CART) which transcription is regulated by cocaine and amphetamine. In addition, other factors are involved such as hormones of the alimentary tract (appetite-stimulating ghrelin and appetite-decreasing cholecystokinin, peptide YY, glucagon like peptide-1, oxyntomodulin, pancreatic peptide, enterostatin and amylin). In this process participates also leptin, an appetite-suppressing hormone produced by adipocytes. The authors focus on other, little-known neurotransmitters involved in the control of appetite: RFamide Peptide (QRFP43) and VGF-Derived Peptide, TLQP-21, as well as xenin, another hunger-decreasing hormone of the alimentary tract.