| Summary: | Chickens in the control group received a standard ration, the first experimental – ration with the addition of tocopherol acetate, the second experimental – ascorbic acid, and the third – a complex of these vitamins. On the basis of the conducted researches the influence of vitamin supplements on the indexes of oxidation intensity of lipid and protein structures was analyzed. The intensity of the processes of oxidative modification of proteins largely depends on the level of vitamins E and C in the ration of broiler chickens. Supplementation with vitamin C and with vitamin E resulted in an inhibitory influence on the content of OMP products, the level of which is largely regulated by the enzyme and non-enzymatic links of the antioxidant protection system. Searches have shown the stimulating influence of the addition of vitamins on the activity of antioxidant enzymes. In particular, SOD activity increased by 19 % on the 34th day, by 32 % on the 41st day, whereas glutathione peroxidase activity was 5.7 and 20.8 %, respectively, compared to the control chickens group. An increase in the activity of antioxidant enzymes occurred against the background of a decrease in the intensity of oxidation processes. At the same time, there was also an increase in the content of recovered glutathione in the blood of chickens of the second and third experimental groups at 34th and 41st days of age. Thereby, searches have shown that supplementing the ration with vitamins E and C with a positive influence on the organism's adaptive capacity and antioxidant potential, which is extremely important to ensure the metabolic homeostasis of chickens during critical periods of their cultivation.
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