Utility of a single adjusting compartment: a novel methodology for whole body physiologically-based pharmacokinetic modelling
<p>Abstract</p> <p>Background</p> <p>There are various methods for predicting human pharmacokinetics. Among these, a whole body physiologically-based pharmacokinetic (WBPBPK) model is useful because it gives a mechanistic description. However, WBPBPK models cannot predi...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-08-01
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| Series: | Theoretical Biology and Medical Modelling |
| Online Access: | http://www.tbiomed.com/content/5/1/19 |