Molecular Dynamics Study of Amyloidogenic Mutants of Human Lysozyme
The mutants of human lysozyme are capable of fibril formation implicated in the etiology of familial systemic or renal amyloidosis. A series of 100 ns thermal unfolding molecular dynamics (MD) simulations with WT human lysozyme and its seven amyloidogenic variants (I56T, D67H, F57I, W64R, Y54N, F57I...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
V.N. Karazin Kharkiv National University Publishing
2019-01-01
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| Series: | East European Journal of Physics |
| Subjects: | |
| Online Access: | https://periodicals.karazin.ua/eejp/article/view/12203 |