Animal Models to Study the Mutational Landscape for Oral Cavity and Oropharyngeal Cancers

Objectives: Cancer is likely caused by alterations in gene structure or expression. Recently, next generation sequencing has documented mutations in 106 head and neck squamous cell cancer genomes, suggesting several new candidate genes. However, it remains difficult to determine which mutations dir...

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Bibliographic Details
Main Authors: Michael T. Spiotto, Matthew Pytynia, Gene-Fu F. Liu, Mark C. Ranck, Ryan Widau
Format: Article
Language:English
Published: Stilus Optimus 2013-01-01
Series:eJournal of Oral Maxillofacial Research
Subjects:
Online Access:http://www.ejomr.org/JOMR/archives/2013/1/e1/v4n1e1ht.htm