Effect of prolonged differentiation on functional maturation of human pluripotent stem cell-derived neuronal cultures

Effect of prolonged differentiation on functional maturation of human pluripotent stem cell-derived neuronal cultures

Long-term neural differentiation of human pluripotent stem cells (hPSCs) is associated with enhanced neuronal maturation, which is a necessity for creation of representative in vitro models. It also induces neurogenic-to-gliogenic fate switch, increasing proportion of endogenous astrocytes formed fr...

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Bibliographic Details
Main Authors:	Tanja Paavilainen, Anssi Pelkonen, Meeri E.-L. Mäkinen, Marja Peltola, Heini Huhtala, Dmitriy Fayuk, Susanna Narkilahti
Format:	Article
Language:	English
Published:	Elsevier 2018-03-01
Series:	Stem Cell Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S1873506118300242

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