RNA sequencing reveals changes in the microRNAome of transdifferentiating hepatic stellate cells that are conserved between human and rat

RNA sequencing reveals changes in the microRNAome of transdifferentiating hepatic stellate cells that are conserved between human and rat

Abstract MicroRNAs are small (~ 22nt long) noncoding RNAs (ncRNAs) that regulate gene expression at the post-transcriptional level. Over 2000 microRNAs have been described in humans and many are implicated in human pathologies including tissue fibrosis. Hepatic stellate cells (HSC) are the major cel...

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Bibliographic Details
Main Authors: Laura Sabater, Luigi Locatelli, Fiona Oakley, Timothy Hardy, Jeremy French, Stuart M. Robinson, Gourab Sen, D. A. Mann, Jelena Mann
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78776-3

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https://doi.org/10.1038/s41598-020-78776-3

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