Isocitrate dehydrogenase mutation in Vibrio anguillarum results in virulence attenuation and immunoprotection in rainbow trout (Oncorhynchus mykiss)
Abstract Background Vibrio anguillarum is an extracellular bacterial pathogen that is a causative agent of vibriosis in finfish and crustaceans with mortality rates ranging from 30% to 100%. Mutations in central metabolism (glycolysis and the TCA cycle) of intracellular pathogens often result in att...
Main Authors: | Xiangyu Mou, Edward J. Spinard, Shelby L. Hillman, David R. Nelson |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-11-01
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Series: | BMC Microbiology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12866-017-1124-1 |
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