Research models and mesenchymal/epithelial plasticity of osteosarcoma

Research models and mesenchymal/epithelial plasticity of osteosarcoma

Abstract Most osteosarcomas (OSs) develop from mesenchymal cells at the bone with abnormal growth in young patients. OS has an annual incidence of 3.4 per million people and a 60–70% 5-year surviving rate. About 20% of OS patients have metastasis at diagnosis, and only 27% of patients with metastati...

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Bibliographic Details
Main Authors: Xiaobin Yu, Jason T. Yustein, Jianming Xu
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Cell & Bioscience
Subjects:
Osteosarcoma
Metastasis
Experimental model
EMT/MET-related process
EMT-TFs
Online Access:https://doi.org/10.1186/s13578-021-00600-w

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