A Systematic Histopathologic Evaluation of Type-A Aortic Dissections Implies a Uniform Multiple-Hit Causation

A Systematic Histopathologic Evaluation of Type-A Aortic Dissections Implies a Uniform Multiple-Hit Causation

(1) Background: The pathophysiologic basis of an acute type A aortic dissection (TAAD) is largely unknown. In an effort to evaluate vessel wall defects, we systematically studied aortic specimens in TAAD patients. (2) Methods: Ascending aortic wall specimens (<i>n</i> = 58, mean age 63 y...

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Bibliographic Details
Main Authors: Nimrat Grewal, Bart J. J. Velders, Adriana C. Gittenberger-de Groot, Robert Poelmann, Robert J. M. Klautz, Thomas J. Van Brakel, Jan H. N. Lindeman
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
acute aortic syndrome
cardiovascular disease
aorta
Online Access:https://www.mdpi.com/2308-3425/8/2/12

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