Downregulation of PAX6 by shRNA inhibits proliferation and cell cycle progression of human non-small cell lung cancer cell lines.

Downregulation of PAX6 by shRNA inhibits proliferation and cell cycle progression of human non-small cell lung cancer cell lines.

The transcription factor PAX6 is primarily expressed in embryos. PAX6 is also expressed in several tumors and plays an oncogenic role. However, little is known about the role of PAX6 in lung cancer.The function of PAX6 in lung cancer cells was evaluated by small interfering RNA-mediated depletion of...

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Bibliographic Details
Main Authors: Xiaoting Zhao, Wentao Yue, Lina Zhang, Li Ma, Wenyun Jia, Zhe Qian, Chunyan Zhang, Yue Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3893268?pdf=render

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