How microRNA and transcription factor co-regulatory networks affect osteosarcoma cell proliferation.

How microRNA and transcription factor co-regulatory networks affect osteosarcoma cell proliferation.

Osteosarcomas (OS) are complex bone tumors with various genomic alterations. These alterations affect the expression and function of several genes due to drastic changes in the underlying gene regulatory network. However, we know little about critical gene regulators and their functional consequence...

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Bibliographic Details
Main Authors: Kathrin Poos, Jan Smida, Michaela Nathrath, Doris Maugg, Daniel Baumhoer, Eberhard Korsching
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3757060?pdf=render

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