Canine Parvovirus is diagnosed and neutralized by chicken IgY-scFv generated against the virus capsid protein

Canine Parvovirus is diagnosed and neutralized by chicken IgY-scFv generated against the virus capsid protein

Abstract Canine parvovirus (CPV) can cause acute and highly contagious bloody enteritis in dog. To obtain antibodies against CPV, hens were immunized with virus-like particles (VLP) of CPV-VP2. The IgY single chain fragment variables (scFv) were generated by T7 phage display system and expressed in...

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Bibliographic Details
Main Authors: Shikun Ge, Long Xu, Ben Li, Fagang Zhong, Xiang Liu, Xiaoying Zhang
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Veterinary Research
Subjects:
IgY-Technology
infectious animal diseases
virus diseases
parvovirus
phage display system
Online Access:http://link.springer.com/article/10.1186/s13567-020-00832-7

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