QSAR Studies on N-aryl Derivative Activity Towards Alzheimer’s Disease

A Quantitative Structure Activity Relationship (QSAR) study has been an attempted on a series of 88 N-aryl derivatives which display varied inhibitory activity towards both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), targets in Alzheimer’s drug discovery. QSAR models were derived f...

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Bibliographic Details
Main Authors: Kamalakaran Anand Solomon, Veluchamy Abirami, Srinivasan Sundararajan
Format: Article
Language:English
Published: MDPI AG 2009-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/14/4/1448/