Prosaposin promotes the proliferation and tumorigenesis of glioma through toll-like receptor 4 (TLR4)-mediated NF-κB signaling pathwayResearch in context

Background: As a neurotrophic factor, prosaposin (PSAP) can exert neuroprotective and neurotrophic effects. It is involved in the occurrence and development of prostate and breast cancer. However, there is no research about the role of PSAP in glioma. Methods: The PSAP overexpressed or silenced glio...

Full description

Bibliographic Details
Main Authors: Yang Jiang, Jinpeng Zhou, Peng Luo, Huiling Gao, Yanju Ma, Yin-Sheng Chen, Long Li, Dan Zou, Ye Zhang, Zhitao Jing
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418304742