Magnetic Alignment of Electrospun Fiber Segments Within a Hydrogel Composite Guides Cell Spreading and Migration Phenotype Switching

Magnetic Alignment of Electrospun Fiber Segments Within a Hydrogel Composite Guides Cell Spreading and Migration Phenotype Switching

Fibrous extracellular matrix (ECM) proteins provide mechanical structure and adhesive scaffolding to resident cells within stromal tissues. Aligned ECM fibers play an important role in directing morphogenetic processes, supporting mechanical loads, and facilitating cell migration. Various methods ha...

Full description

Bibliographic Details
Main Authors:	Harrison L. Hiraki, Daniel L. Matera, Michael J. Rose, Robert N. Kent, Connor W. Todd, Mark E. Stout, Anya E. Wank, Maria C. Schiavone, Samuel J. DePalma, Alexander A. Zarouk, Brendon M. Baker
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-06-01
Series:	Frontiers in Bioengineering and Biotechnology
Subjects:	electrospinning fiber alignment hydrogel epithelial cell migration tendon
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2021.679165/full

Similar Items

Tissue Engineering Cartilage with a Composite Electrospun and Hydrogel Scaffold
by: Wright, Lee David
Published: (2014)

Conformal Fabrication of an Electrospun Nanofiber Mat on a 3D Ear Cartilage-Shaped Hydrogel Collector Based on Hydrogel-Assisted Electrospinning
by: Jin Yeong Song, et al.
Published: (2021-07-01)

Dual-layer aligned-random nanofibrous scaffolds for improving gradient microstructure of tendon-to-bone healing in a rabbit extra-articular model
by: Cai J, et al.
Published: (2018-06-01)

Physicochemical Properties and Biocompatibility of Electrospun Polycaprolactone/Gelatin Nanofibers
by: Wei Lee Lim, et al.
Published: (2021-04-01)

Highly aligned electrospun nanofibers by hot-drawing
by: Liu Hong-Ying, et al.
Published: (2015-01-01)

Aligned electrospun polymer fibres for skeletal muscle regeneration
by: KJ Aviss, et al.
Published: (2010-05-01)

Ultra-Sonographic Evaluation and Growth Factors Measurement of Using Tendon Derived Hydrogel and Hyaluronic Acid in Tendon Repair in Rams
by: Omar Tariq Hammoodi, et al.
Published: (2019-12-01)

Biological Performance of Electrospun Polymer Fibres
by: Ivan Joseph Hall Barrientos, et al.
Published: (2019-01-01)

Tough Hydrogels Based on Maleic Anhydride, Bulk Properties Study and Microfiber Formation by Electrospinning
by: Faiza Bettahar, et al.
Published: (2021-03-01)

Mechanical and Dielectric Properties of Aligned Electrospun Fibers
by: Blesson Isaac, et al.
Published: (2021-01-01)

Amphiphilic electrospun fibres of poly(methacrylic acid)-graft-poly(dimethylsiloxane) copolymers as a means to controlling electrospun fibre morphology and obtaining nanofibre hydrogels
by: Meltz, Freda-Jean
Published: (2014)

Controlling the spatial deposition of electrospun fibre
by: Abdul Hamid, Nurfaizey
Published: (2014)

Resorbable electrospun polydioxanone fibres modify the behaviour of cells from both healthy and diseased human tendons
by: A Kendal, et al.
Published: (2017-02-01)

Magnetic Nanoparticle-Mediated Orientation of Collagen Hydrogels for Engineering of Tendon-Mimetic Constructs
by: Broomhall, T.J, et al.
Published: (2022)

Tendon Biomimetic Electrospun PLGA Fleeces Induce an Early Epithelial-Mesenchymal Transition and Tenogenic Differentiation on Amniotic Epithelial Stem Cells
by: Valentina Russo, et al.
Published: (2020-01-01)

Evaluating the Effect of Electrospun Polyvinyl Alcohol Nanofiber Containing Eucalyptus globules Extract on the Healing of Experimental Achilles Tendon Injury in Rat
by: Seyed Mohammad Ali Sadat-Hosseini, et al.
Published: (2021-05-01)

Biofabrication of Electrospun Scaffolds for the Regeneration of Tendons and Ligaments
by: Alberto Sensini, et al.
Published: (2018-10-01)

Regulation of ERK1/2 and SMAD2/3 Pathways by Using Multi-Layered Electrospun PCL–Amnion Nanofibrous Membranes for the Prevention of Post-Surgical Tendon Adhesion
by: Liu C, et al.
Published: (2020-02-01)

Polylactide/Hydroxyapatite Nonwovens Incorporated into Chitosan/Graphene Materials Hydrogels to Form Novel Hierarchical Scaffolds
by: Karolina Kosowska, et al.
Published: (2020-03-01)

In vitro behavior of tendon stem/progenitor cells on bioactive electrospun nanofiber membranes for tendon-bone tissue engineering applications
by: Lin Y, et al.
Published: (2019-07-01)

Tuning the Structure of Nylon 6,6 Electrospun Bundles to Mimic the Mechanical Performance of Tendon Fascicles
by: Alberto Sensini, et al.
Published: (2021-04-01)

Enhancement of Migration and Tenogenic Differentiation of Macaca Mulatta Tendon-Derived Stem Cells by Decellularized Tendon Hydrogel
by: Liang-Ju Ning, et al.
Published: (2021-04-01)

Toward Morphologically Relevant Extracellular Matrix in Vitro Models: 3D Fiber Reinforced Hydrogels
by: Ashok Williams, et al.
Published: (2018-07-01)

Promoting tendon to bone integration using graphene oxide-doped electrospun poly(lactic-co-glycolic acid) nanofibrous membrane
by: Su W, et al.
Published: (2019-03-01)

Electrospun PLGA Fiber Diameter and Alignment of Tendon Biomimetic Fleece Potentiate Tenogenic Differentiation and Immunomodulatory Function of Amniotic Epithelial Stem Cells
by: Mohammad El Khatib, et al.
Published: (2020-05-01)

Effect of Nanofibrillated Cellulose Content on the Temperature and Near Infrared Responses of Polyvinyl Butyral Nanofibers-Containing Bilayer Hydrogel System
by: Qian Zhao, et al.
Published: (2017-07-01)

3D Printing and Electrospinning of Composite Hydrogels for Cartilage and Bone Tissue Engineering
by: Arianna De Mori, et al.
Published: (2018-03-01)

Thermosensitive Chitosan–Gelatin–Glycerol Phosphate Hydrogels as Collagenase Carrier for Tendon–Bone Healing in a Rabbit Model
by: Yu-Min Huang, et al.
Published: (2020-02-01)

Aligned electrospun cellulose scaffolds coated with rhBMP-2 for both in vitro and in vivo bone tissue engineering
by: Zhang, X., et al.
Published: (2019)

A facile route for controlled alignment of carbon nanotube-reinforced, electrospun nanofibers using slotted collector plates
by: G. R. Rakesh, et al.
Published: (2015-02-01)

Alignment of Electrospun Nanofibers and Prediction of Electrospinning Linear Speed Using a Rotating Jet
by: M. Khamforoush, et al.
Published: (2009-12-01)

Hydrogel Nanofibers from Carboxymethyl Sago Pulp and Its Controlled Release Studies as a Methylene Blue Drug Carrier
by: Nafeesa Mohd Kanafi, et al.
Published: (2019-06-01)

Hybrid Polyester-Hydrogel Electrospun Scaffolds for Tissue Engineering Applications
by: Ana Rita Gonçalves de Pinho, et al.
Published: (2019-09-01)

Controlled deposition and alignment of electrospun PMMA-g-PDMS nanofibers by novel electrospinning setups
by: Haseeb, Bashar
Published: (2011)

Investigation of the Mechanical and Dynamic-Mechanical Properties of Electrospun Polyvinylpyrrolidone Membranes: A Design of Experiment Approach
by: Andrea Dodero, et al.
Published: (2020-07-01)

In Situ Preparation of Novel Porous Nanocomposite Hydrogel as Effective Adsorbent for the Removal of Cationic Dyes from Polluted Water
by: Badr M. Thamer, et al.
Published: (2020-12-01)

Enhancement of Rotator Cuff Healing with Farnesol-Impregnated Gellan Gum/Hyaluronic Acid Hydrogel Membranes in a Rabbit Model
by: Yen-Hung Lin, et al.
Published: (2021-06-01)

The effect of electrospun fibre alignment on the behaviour of rat periodontal ligament cells
by: S Shang, et al.
Published: (2010-04-01)

Design of a Novel Oxygen Therapeutic Using Polymeric Hydrogel Microcapsules Mimicking Red Blood Cells
by: Amanda Cherwin, et al.
Published: (2019-11-01)

Strategies for the Fabrication of Cellularized Micro-Fiber/Hydrogel Composites for Ligament Tissue Engineering
by: Thayer, Patrick Scott
Published: (2017)