Specific immunological areactivity formation during gestation period in pregnant sows

• Main Authors: Agarkov Alexander, Dmitriev Anatoly, Kvochko Andrey, Grudeva Elena, Agarkov Nikolay, Onishchenko Artem
• Format: Article
• Language: English
• Published: EDP Sciences 2020-01-01
• Series: E3S Web of Conferences
• Online Access: https://www.e3s-conferences.org/articles/e3sconf/pdf/2020/70/e3sconf_itse2020_06002.pdf

Changes in immunological reactivity to viral and bacterial antigens may cause increased susceptibility to infectious diseases. Different levels of this condition in newborn and adult animal organisms should be based on the fact that the fetus and newborn after birth first comes into contact with the antigen, while the adult body already has partial sensitization. Chronic carrier of pathogens in animals and their influence on the spread of the infectious process is an urgent problem of modern veterinary medicine. The possibility of vaccination in newborns is limited by the presence of maternal antibodies that have an immunosuppressive effect. A high level of functional reserves of the pregnant body is important in the prevention of intrauterine infection. On the one hand, infection in the prenatal period of development affects the processes of growth and development of the fetus, on the other hand, during this period, the mother's body is isoimmunized by fetal antigens, accompanied by increased sensitivity of the body with the predominant manifestation of cellular phenomena in the absence of enhanced antibody synthesis.