Glucose-mediated proliferation of a gut commensal bacterium promotes Plasmodium infection by increasing mosquito midgut pH

Summary: Plant-nectar-derived sugar is the major energy source for mosquitoes, but its influence on vector competence for malaria parasites remains unclear. Here, we show that Plasmodium berghei infection of Anopheles stephensi results in global metabolome changes, with the most significant impact o...

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Bibliographic Details
Main Authors: Mengfei Wang, Yanpeng An, Li Gao, Shengzhang Dong, Xiaofeng Zhou, Yuebiao Feng, Penghua Wang, George Dimopoulos, Huiru Tang, Jingwen Wang
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721003065