The application of aspirin in pregnancy-related complications

• Main Authors: Lu-Yu Ruan, Zhen-Zhen Lai, Hui-Li Yang, Shao-Liang Yang, Si-Yao Ha, Jia-Wei Shi, Hui-Hui Shen, Ming-Qing Li
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2020-01-01
• Series: Reproductive and Developmental Medicine
• Subjects: abortion; antiphospholipid antibodies; aspirin; fetal growth restriction; preeclampsia; pregnancy; preterm birth; systemic lupus erythematosus
• Online Access: http://www.repdevmed.org/article.asp?issn=2096-2924;year=2020;volume=4;issue=3;spage=184;epage=190;aulast=Ruan

Aspirin, one of the most widely applied medicines, not only possesses the effects on reducing fever, anti-vascular hyperplasia, and anti-inflammation, but also has the capacity of preventing platelet aggregation. So far, it is acceptable to adopt aspirin, especially low-dose aspirin (LDA), to prevent pregnancy-related complications, such as pregnancy complicated by antiphospholipid syndrome, systemic lupus erythematosus, or preeclampsia; unexplained recurrent spontaneous abortion; fetal growth restriction; and preterm birth. In this article, we reviewed the possible mechanism of action and applications of aspirin in these pregnancy-related complications.