Co-stimulation of PAFR and CD36 is required for oxLDL-induced human macrophages activation.

Co-stimulation of PAFR and CD36 is required for oxLDL-induced human macrophages activation.

The oxidative process of LDL particles generates molecules which are structurally similar to platelet-activating factor (PAF), and some effects of oxidized LDL (oxLDL) have been shown to be dependent on PAF receptor (PAFR) activation. In a previous study, we showed that PAFR is required for upregula...

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Bibliographic Details
Main Authors: Francisco J O Rios, Mariana M Koga, Matheus Ferracini, Sonia Jancar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3343035?pdf=render

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http://europepmc.org/articles/PMC3343035?pdf=render

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