Coagulopathy: Another side effect of coronavirus infection

• Main Authors: Fatemeh Sadoughi, Parisa Maleki Dana, Jamal Hallajzadeh, Zatollah Asemi, Mohammad Ali Mansournia, Bahman Yousefi
• Format: Article
• Language: English
• Published: Tabriz University of Medical Sciences 2021-02-01
• Series: Journal of Cardiovascular and Thoracic Research
• Subjects: sars; covid-19; cov; heparin; dic; pic; vte
• Online Access: https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-13-15.pdf

Recently, coronavirus disease 2019 (COVID-19) has been considered as a major health problem around the globe. This severe acute respiratory syndrome has a bunch of features, such as high transmission rate, which are adding to its importance. Overcoming this disease relies on a complete understanding of the viral structure, receptors, at-risk cells or tissues, and pathogenesis. Currently, researches have shown that besides the lack of a proper anti-viral therapeutic method, complications provided by this virus are also standing in the way of decreasing its mortality rate. One of these complications is believed to be a hematologic manifestation. Commonly, three kinds of coagulopathies are detected in COVID-19 patients: disseminated intravascular coagulation (DIC), pulmonary embolism (PE), and deep vein thrombosis (DVT). In this paper, we have reviewed the relation between these conditions and coronavirus-related diseases pathogenesis, severity, and mortality rate.