Unusual intron conservation near tissue-regulated exons found by splicing microarrays.
Alternative splicing contributes to both gene regulation and protein diversity. To discover broad relationships between regulation of alternative splicing and sequence conservation, we applied a systems approach, using oligonucleotide microarrays designed to capture splicing information across the m...
Main Authors: | Charles W Sugnet, Karpagam Srinivasan, Tyson A Clark, Georgeann O'Brien, Melissa S Cline, Hui Wang, Alan Williams, David Kulp, John E Blume, David Haussler, Manuel Ares |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2006-01-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC1331982?pdf=render |
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