Unusual intron conservation near tissue-regulated exons found by splicing microarrays.

Alternative splicing contributes to both gene regulation and protein diversity. To discover broad relationships between regulation of alternative splicing and sequence conservation, we applied a systems approach, using oligonucleotide microarrays designed to capture splicing information across the m...

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Bibliographic Details
Main Authors: Charles W Sugnet, Karpagam Srinivasan, Tyson A Clark, Georgeann O'Brien, Melissa S Cline, Hui Wang, Alan Williams, David Kulp, John E Blume, David Haussler, Manuel Ares
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1331982?pdf=render