The impairment of osteogenesis in bone sialoprotein (BSP) knockout calvaria cell cultures is cell density dependent.

Bone sialoprotein (BSP) belongs to the "small integrin-binding ligand N-linked glycoprotein" (SIBLING) family, whose members interact with bone cells and bone mineral. BSP is strongly expressed in bone and we previously showed that BSP knockout (BSP-/-) mice have a higher bone mass than wi...

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Bibliographic Details
Main Authors: Guenaelle Bouet, Wafa Bouleftour, Laura Juignet, Marie-Thérèse Linossier, Mireille Thomas, Arnaud Vanden-Bossche, Jane E Aubin, Laurence Vico, David Marchat, Luc Malaval
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0117402